I’ve had this issue since I started using S1 about 4 years ago. I wrote to support and also wrote about it in this forum but never got to the bottom of it.
The difficulty with reproducing a bug that happens when you least expect it is just that. There was never a rhyme or reason I would flick to the mix window and see all my busses that I had organized in my template next to all their respective channels just scattered randomly everywhere.
I was also asked to reproduce it (which can sometimes feel like them saying “if you can’t make it happen at will then does it actually exist!?” ) and I never could... but bet you’re bottom dollar it would happen once a day.

I think we can take comfort in the fact that this happens to quite a few people and the common denominator seems to be S1 rather than a 3rd party plugin or our systems... here’s hoping it gets fixed.