Just wanted to note my experience if useful.

I have StudioLive 32SC with Notion and Studio One. I've had many pop and click issues, especially during playback with Notion and have just suffered through it.

I use Norton Antivirus and had previously added various paths as "safe" to try to solve the problem but that didn't seem to work (it has for others, perhaps I just need to find the right path). However today I just clicked right on the Norton Security small window-corner icon and disabled the Smart Firewall. Incredibly the problem went away. I've now disabled that permanently, hope it doesn't come back.