Anybody been in this situation before?

Any time I use a Sampler / Simpler instrument that accesses samples or whatnot, I get a hard disk overload at every note on message played from Studio One going to Ableton

Studio One rewire master
Ableton 10 rewire slave
Ableton 10 being used as an instrument in SO
Audio running back to Studio One

I've tested it on different computers (mac laptop, mac desktop), interfaces, buffer settings, different settings in Studio One regarding monitoring and low latency modes. Always an HD overload in ableton at every note on. I have also tested different sample locations. Tested it with samples on the same disk as ableton, tested it with instruments located on an external SSD (through USB3)

CPU usage seems fine and playing virtual instruments in Ableton works great.

There's something about playing sample base instruments over Rewire that causes a Hard Disk Overload. the same patches do not overload when played in Ableton directly (even if it is a Rewire slave).

Thoughts?